H2N2V1, Main, Exploration, bibRecord, 002771

Recombination of human influenza A viruses in nature.

Identifieur interne : 002771 ( Main/Exploration ); précédent : 002770; suivant : 002772

Recombination of human influenza A viruses in nature.

Auteurs : W J Bean ; N J Cox ; A P Kendal

Source :

Nature [ 0028-0836 ] ; 1980.

RBID : pubmed:7366737

Descripteurs français

KwdFr :
- ARN viral (génétique), Antigènes de surface (génétique), Antigènes viraux (génétique), Flambées de maladies, Grippe humaine (microbiologie), Gènes viraux, Humains, Protéines virales (génétique), Recombinaison génétique, Virus de la grippe A (génétique), Virus de la grippe A (immunologie).
MESH :
- génétique : ARN viral, Antigènes de surface, Antigènes viraux, Protéines virales, Virus de la grippe A.
- immunologie : Virus de la grippe A.
- microbiologie : Grippe humaine.
- Flambées de maladies, Gènes viraux, Humains, Recombinaison génétique.

English descriptors

KwdEn :
- Antigens, Surface (genetics), Antigens, Viral (genetics), Disease Outbreaks, Genes, Viral, Humans, Influenza A virus (genetics), Influenza A virus (immunology), Influenza, Human (microbiology), RNA, Viral (genetics), Recombination, Genetic, Viral Proteins (genetics).
MESH :
- chemical , genetics : Antigens, Surface, Antigens, Viral, RNA, Viral, Viral Proteins.
- genetics : Influenza A virus.
- immunology : Influenza A virus.
- microbiology : Influenza, Human.
- Disease Outbreaks, Genes, Viral, Humans, Recombination, Genetic.

Abstract

In 1977, a unique event occurred in the epidemiology of influenza when a virus of the influenza A (H1N1) subtype, similar to a virus that had occurred in 1950, reappeared and caused worldwide epidemics but did not replace the prevailing influenza A (H2N2) subtype. Consequently, the two viruses co-circulated throughout the world and mixed infection of some individuals with both virus strains was detected, raising the possiblitity that recombination between the two strains might affect the future epidemiological behaviour of influenza. Serological analysis of virus isolates from influenza outbreaks during the winter of 1978-79, however, failed to detect any antigenic hybrids (H2N1 or H1N2). The investigation described here, was therefore, undertaken to detect recombinants among recent isolates of the H1N1 and H3N1 serotypes, involving genes coding for other than the surface proteins by RNA-RNA hybridisation. We report here the genetic characterisation of recombinants of both antigenic types.

DOI: 10.1038/284638a0
PubMed: 7366737

Affiliations:

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<term>Antigènes viraux</term>
<term>Protéines virales</term>
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<front><div type="abstract" xml:lang="en">In 1977, a unique event occurred in the epidemiology of influenza when a virus of the influenza A (H1N1) subtype, similar to a virus that had occurred in 1950, reappeared and caused worldwide epidemics but did not replace the prevailing influenza A (H2N2) subtype. Consequently, the two viruses co-circulated throughout the world and mixed infection of some individuals with both virus strains was detected, raising the possiblitity that recombination between the two strains might affect the future epidemiological behaviour of influenza. Serological analysis of virus isolates from influenza outbreaks during the winter of 1978-79, however, failed to detect any antigenic hybrids (H2N1 or H1N2). The investigation described here, was therefore, undertaken to detect recombinants among recent isolates of the H1N1 and H3N1 serotypes, involving genes coding for other than the surface proteins by RNA-RNA hybridisation. We report here the genetic characterisation of recombinants of both antigenic types.</div>
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Serveur d'exploration H2N2

Recombination of human influenza A viruses in nature.

Recombination of human influenza A viruses in nature.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration H2N2
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